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Definition of Rhabdomyolysis

Babylon English

(Medicine) disintegration of skeletal muscle tissue as a result of electrocution or prolonged exposure to toxins (characterized by excretion of myoglobin in the urine)
Rhabdomyolysis Definition from Medicine Dictionaries & Glossaries
Dictionary of Medicine (Shahram)
A condition whereby skeletal muscle is broken down, releasing intracellular (inside the cell) muscle enzymes and electrolytes. The major risks of this condition are two fold: one is obviously muscle breakdown and the other is kidney failure. The myoglobin, an intracellular component, is toxic to the kidneys and may lead to kidney failure. Rhabdomyolysis is relatively uncommon, but most often occurs as the result of extensive muscle damage, for example crush injury or electrical shock. Other causes many be drug or toxin, for example many of the cholesterol lowering medications have the potential to cause this disorder. Underlying diseases can also lead to rhabdomyolysis, including collagen vascular diseases (such as systemic lupus erythematosus) and others, which if left untreated may also cause this muscle degradation.
Rhabdomyolysis Definition from Encyclopedia Dictionaries & Glossaries
Wikipedia English - The Free Encyclopedia
Rhabdomyolysis is a condition in which damaged skeletal muscle tissue (Greek: ῥαβδω rhabdo- striped μυς myo- muscle) breaks down (Greek: λύσις –lysis) rapidly. Breakdown products of damaged muscle cells are released into the bloodstream; some of these, such as the protein myoglobin, are harmful to the kidneys and may lead to kidney failure. The severity of the symptoms, which may include muscle pains, vomiting and confusion, depends on the extent of muscle damage and whether kidney failure develops. The muscle damage may be caused by physical factors (e.g., crush injury, strenuous exercise), medications, drug abuse, and infections. Some people have a hereditary muscle condition that increases the risk of rhabdomyolysis. The diagnosis is usually made with blood tests and urinalysis. The mainstay of treatment is generous quantities of intravenous fluids, but may include dialysis or hemofiltration in more severe cases.

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