Definition of Nucleophilic aromatic substitution
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Nucleophilic aromatic substitution Definition from Encyclopedia Dictionaries & Glossaries
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A nucleophilic aromatic substitution is a substitution reaction in organic chemistry in which the nucleophile displaces a good leaving group, such as a halide, on an aromatic ring. There are 6 nucleophilic substitution mechanisms encountered with aromatic systems:
- the SNAr (addition-elimination) mechanism
- the aromatic SN1 mechanism encountered with diazonium salts
- the benzyne mechanism
- the free radical SRN1 mechanism
- the ANRORC mechanism
- Vicarious nucleophilic substitution.
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