Definition of Metabotropic receptor

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Metabotropic receptor
a receptor molecule for neurotransmitters that is located in the postsynaptic membrane and, after binding to the transmitter, activates G proteins and other membrane-bound molecules.

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Metabotropic receptor Definition from Encyclopedia Dictionaries & Glossaries

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Metabotropic receptor
Metabotropic receptor is a subtype of membrane receptors at the surface or in vesicles of eukaryotic cells.

In the nervous system, based on their structural and functional characteristics, neurotransmitter receptors can be classified into two broad categories: metabotropic and ionotropic receptors. In contrast to the latter, metabotropic receptors do not form an ion channel pore; rather, they are indirectly linked with ion-channels on the plasma membrane of the cell through signal transduction mechanisms.


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