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Leucovorin Definition from Medicine Dictionaries & Glossaries
A drug used to protect normal cells from high doses of the anticancer drug methotrexate. It is also used to increase the antitumor effects of fluorouracil and tegafur-uracil, an oral treatment alternative to intravenous fluorouracil.
A Service of the National Cancer Institute.
a derivative of folic acid, a member of the vitamin B complex. Leucovorin protects cells from the cytotoxic effects of certain drugs (e.g., dapsone, trimetrexate) and is used to prevent drug-induced anemia.
AegisLeucovorin Definition from Encyclopedia Dictionaries & Glossaries
Folinic acid (INN) or leucovorin (USAN), generally administered as calcium or sodium folinate (or leucovorin calcium/sodium), is an adjuvant used in cancer chemotherapy involving the drug methotrexate. It is also used in synergistic combination with the chemotherapy agent 5-fluorouracil.
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