Hippuric Acid
A white crystalline nitrogenous acid formed in the liver as a detoxication product of benzoic acid and present in the urine of herbivorous animals and in small quantity in human urine | ||||
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Hippuric acid Definition from Language, Idioms & Slang Dictionaries & Glossaries
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hippuric acid
hippuric acid
hippuric \hip*pu"ric\ (?), a. [gr. "i`ppos horse + o"y`ron urine: cf. f. hippurique.] (physiol. chem.) obtained from the urine of horses; as, hippuric acid.
hippuric acid
hippuric \hip*pu"ric\ (?), a. [gr. "i`ppos horse + o"y`ron urine: cf. f. hippurique.] (physiol. chem.) obtained from the urine of horses; as, hippuric acid.
Hippuric acid Definition from Encyclopedia Dictionaries & Glossaries
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Hippuric acid
Hippuric acid (Gr. hippos, horse, ouron, urine) is an organic acid found in the urine of horses and other herbivores. High concentrations of hippuric acid can also indicate a toluene intoxication.
When many aromatic compounds such as benzoic acid and toluene are taken internally, they are converted to hippuric acid by reaction with the amino acid glycine. Justus von Liebig in 1829 showed that hippuric acid differed from benzoic acid, and in 1839 determined its constitution, while in 1873 Victor Dessaignes synthesized it by the action of benzoyl chloride on the zinc salt of glycine. It is also formed by heating benzoic anhydride with glycine, and by heating benzamide with monochloroacetic acid.
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