Gene conversion
Partial sequence transfer from one allele to another (interallelic recombination). It is the most common mechanism, especially for the HLA-B locus, in the generation of a new MHC allele. Less common are conversions between alleles of different MHC loci (intergenic conversion). | ||||
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Gene conversion Definition from Encyclopedia Dictionaries & Glossaries
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Gene conversion
Gene conversion is an error in DNA genetic recombination, which occurs during meiotic division. It is a process by which DNA sequence information is transferred from one DNA helix (which remains unchanged) to another DNA helix, whose sequence is altered. It is one of the ways a gene may be mutated to create a cancerous gene.
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