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Dendritic cells Definition from Science & Technology Dictionaries & Glossaries
BioProcess International™ Glossary
the most immune-stimulating cells in the human body, occurring naturally in tissues that contact the exterior environment: in the skin and the lining of nose, lungs, stomach, and intestines; they get their name from their long tentacle-like arms, called dendrites, and form from circulating monocytes; they function as antigen-presenting cells and attract invading viruses and bacteria, then cut those proteins into short, linear peptide pieces (see epitope), and carry the fragments on their surfaces (enmeshed in their tentacles) through the blood stream to lymph nodes to activate B cells, helper T cells, and CTLs; only dendritic cells can activate a helper T cell that has never before encountered a particular antigen before. (see: epitope)Copyright © 2002 - 2006, BioProcess International™. All rights reserved.
Dendritic cells Definition from Encyclopedia Dictionaries & Glossaries
Wikipedia English - The Free Encyclopedia
Dendritic cells (DCs) are immune cells forming part of the mammalian immune system. Their main function is to process antigen material and present it on the surface to other cells of the immune system. That is, dendritic cells function as antigen-presenting cells. They act as messengers between the innate and adaptive immunity.
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Dendritic cells Definition from Medicine Dictionaries & Glossaries
Glossary of HIV/AIDS-Related Terms
Patrolling immune system cells that may begin the HIV disease process by carrying the virus from the site of the infection to the lymph nodes<!-- (see) -->, where other immune cells become infected. Dendritic cells travel through the body and bind to foreign invaders -- such as HIV -- especially in external tissues, such as the skin and the membranes of the gut, lungs, and reproductive tract. They then ferry the foreign substance to the lymph nodes to stimulate T cells<!-- (see) --> and initiate an immune response. In laboratory experiments, the dendritic cells that carry HIV also bind to CD4+ T cells<!-- (see) -->, thereby allowing HIV to infect the CD4+ T cells. CD4+ T cells are the primary immune system cells targeted by HIV and depleted during HIV infection.ATIS