UGT1A1
A substance that is being studied as a treatment for cancer. It is an enzyme produced by the liver and intestine. | ||||
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UGT1A1 Definition from Encyclopedia Dictionaries & Glossaries
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UGT1A1
UGT1A1 is a gene associated with Crigler-Najjar syndrome, and a common splice variant is associated with serious side effects to the common chemotherapeutic drug irinotecan. The primary function of the gene's protien product is uridine diphospate glycosyltrasnferase 1 and is involved in the conversion of lipophilic molocules to water soluble substances suitable for excretion via substrate glycosylation.
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