MGUS
Monoclonal gammopathy of undetermined significance. A benign condition in which there is a high level of a protein called M protein in the blood. Patients with MGUS are at an increased risk of developing cancer. | ||||
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MGUS Definition from Encyclopedia Dictionaries & Glossaries
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Monoclonal gammopathy of undetermined significance
Monoclonal gammopathy of undetermined significance (MGUS, unknown or uncertain may be substituted for undetermined) or benign monoclonal gammopathy is a condition in which a low or non-quantifiable level of a monoclonal paraprotein is detected in the blood by means of protein electrophoresis. In addition, some patients develop a polyneuropathy (damage to peripheral nerves) or other problems related to the secreted antibody. MGUS is distinct from multiple myeloma, as described below.
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