IL-12
Interleukin-12. A type of biological response modifier (a substance that can improve the body's natural response to disease) that enhances the ability of the immune system to kill tumor cells and may interfere with blood flow to the tumor. These substances are normally produced by the body. They are also made in the laboratory for use in treating cancer and other diseases. | ||||
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IL-12 definition was found in categories: Medicine(2) Encyclopedia(1)
IL-12 Definition from Medicine Dictionaries & Glossaries
| Aids Glossary |
interleukin 12
a cytokine produced by lymphocytes (e.g., monocytes, macrophages, dendritic cells, neutrophils) that activates natural killer cells and cytotoxic T-lymphocytes and induces the production of interferon-gamma. IL-12 is associated with the cell-mediated (TH1) immune response. Recombinant IL-12 is under study as a immunomodulatory treatment for HIV disease.
a cytokine produced by lymphocytes (e.g., monocytes, macrophages, dendritic cells, neutrophils) that activates natural killer cells and cytotoxic T-lymphocytes and induces the production of interferon-gamma. IL-12 is associated with the cell-mediated (TH1) immune response. Recombinant IL-12 is under study as a immunomodulatory treatment for HIV disease.
| Glossary of HIV/AIDS-Related Terms |
INTERLEUKIN-12
A cytokine released by macrophage<!-- (see) --> in response to infection that promotes the activation of cell-mediated immunity. Specifically, IL-12 triggers the maturation of Thl<!-- (see) --> CD4 cells, specific cytotoxic T lymphocyte responses, and an increase in the activity of NK cells<!-- (see) -->. IL-12 is under study as an immunotherapy<!-- (see) --> in HIV infection.
A cytokine released by macrophage<!-- (see) --> in response to infection that promotes the activation of cell-mediated immunity. Specifically, IL-12 triggers the maturation of Thl<!-- (see) --> CD4 cells, specific cytotoxic T lymphocyte responses, and an increase in the activity of NK cells<!-- (see) -->. IL-12 is under study as an immunotherapy<!-- (see) --> in HIV infection.
IL-12 Definition from Encyclopedia Dictionaries & Glossaries
| Wikipedia English - The Free Encyclopedia |
Interleukin 12
Interleukin 12 (IL-12) is an interleukin that is naturally produced by macrophages and human B-lymphoblastoid cells (NC-37) in response to antigenic stimulation.
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