Definition of Hnpcc

NCI Dictionary of Cancer Terms
HNPCC
Hereditary nonpolyposis colon cancer. An inherited disorder in which affected individuals have a higher-than-normal chance of developing colorectal cancer and certain other types of cancer, often before the age of 50. Also called Lynch syndrome.

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HNPCC Definition from Encyclopedia Dictionaries & Glossaries

Wikipedia English - The Free Encyclopedia
Hereditary nonpolyposis colorectal cancer
Hereditary nonpolyposis colorectal cancer (HNPCC), also known as Lynch syndrome, is characterized by an increased risk of colorectal cancer and other cancers of the endometriumovarystomachsmall intestinehepatobiliary tract, upper urinary tract, brain, and skin. HNPCC is subdivided into Lynch Syndrome I (familial colon cancer) and Lynch Syndrome II (other cancer of the gastrointestinal system or the reproductive system). The increased risk for these cancers is due to inherited mutations that degrade the self-repair capability of DNA.

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