CD40-ligand
A substance that is being studied in the treatment of cancer. It binds to certain immune cells and may suppress cancer growth. | ||||
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CD40-ligand Definition from Encyclopedia Dictionaries & Glossaries
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CD154
CD154, also called CD40 ligand or CD40L, is a protein that is primarily expressed on activated T cells and is a member of the TNF family of molecules. It binds to CD40 on antigen presenting cells (APC) which leads to many effects depending on the target cell type. In general, CD40L plays the role of a costimulatory molecule and induces activation in APC in association with T cell receptor stimulation by MHC molecules on the APC.
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