alpha-fetoprotein
n. (Medicine) AFP, protein produced by a fetus during development and is found in amniotic fluid and the mother's bloodstream; protein produced by the liver cells; protein found in the flow of blood of men suffering from non seminomatous testicular cancer | ||||
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Alpha-fetoprotein definition was found in categories: Language, Idioms & Slang(1) Medicine(6) Encyclopedia(1)
Alpha-fetoprotein Definition from Language, Idioms & Slang Dictionaries & Glossaries
| WordNet 2.0 |
alpha fetoprotein
Noun
1. an abnormally large amount of this fetoprotein in the fetus can signal an abnormality of the neural tube (as spina bifida or anencephaly)
(synonym) alpha foetoprotein, AFP
(hypernym) fetoprotein, foetoprotein
Noun
1. an abnormally large amount of this fetoprotein in the fetus can signal an abnormality of the neural tube (as spina bifida or anencephaly)
(synonym) alpha foetoprotein, AFP
(hypernym) fetoprotein, foetoprotein
Alpha-fetoprotein Definition from Medicine Dictionaries & Glossaries
| NCI Dictionary of Cancer Terms |
alpha-fetoprotein
[AL-fa-FEE-toe-PRO-teen]
AFP. A protein normally produced by a fetus. AFP levels are usually undetectable in the blood of healthy adult men or women (who are not pregnant). An elevated level of AFP suggests the presence of either a primary liver cancer or germ cell tumor.
[AL-fa-FEE-toe-PRO-teen]
AFP. A protein normally produced by a fetus. AFP levels are usually undetectable in the blood of healthy adult men or women (who are not pregnant). An elevated level of AFP suggests the presence of either a primary liver cancer or germ cell tumor.
| Dictionary of Medicine (Shahram) |
alpha-fetoprotein
noun
protein found in the amniotic fluid when the fetus has an open neurological deficiency such as meningomyelocele
noun
protein found in the amniotic fluid when the fetus has an open neurological deficiency such as meningomyelocele
| Hepatitis Central (TM) Liver Disease Medical Glossary |
Alpha-Fetoprotein
A fetal blood protein present abnormally in adults with some forms of cancer, such as liver cancer
¯ (alpha) Level--The probability of a false positive result, or of rejecting the hypothesis of no treatment difference when there is no real difference or of a false positive. Also referred to as the probability of a type I error
¯ (alpha) Spending Function--A function or rule that governs how the total ¯ level or probability of a type I error can be spread out over the interim analysis. Limits the chance of a false positive result when trial data is looked at multiple times. Can be used to set up guidelines for trial monitoring
A fetal blood protein present abnormally in adults with some forms of cancer, such as liver cancer
¯ (alpha) Level--The probability of a false positive result, or of rejecting the hypothesis of no treatment difference when there is no real difference or of a false positive. Also referred to as the probability of a type I error
¯ (alpha) Spending Function--A function or rule that governs how the total ¯ level or probability of a type I error can be spread out over the interim analysis. Limits the chance of a false positive result when trial data is looked at multiple times. Can be used to set up guidelines for trial monitoring
| Terms and Definitions |
Alpha-fetoprotein (AFP)
A protein excreted by the fetus into the amniotic fluid and from there into the mother's bloodstream through the placenta.
A protein excreted by the fetus into the amniotic fluid and from there into the mother's bloodstream through the placenta.
| The TCRC Glossary for Testicular Cancer and Other Related Conditons |
Alpha-fetoprotein
AFP is a protein found in the bloodstream of some men with testicular cancer. The level rises when the cancer is growing and falls when the cancer is shrinking or has been surgically removed, so a blood test can possibly measure the progress of the disease and success of treatment. Because of this behavior, it is referred to as a tumor marker. Elevated levels of AFP occur in 75 per cent of patients with teratocarcinoma, embryonal cell carcinoma, and yolk sac carcinoma. (However, increased levels of AFP are also found in patients with liver diseases, such as cirrhosis, acute and chronic hepatitis and hepatic necrosis. ) The serum half life of AFP is 5 to 7 days, which implies that elevated levels of AFP should fall by one half of the initial level per week and should return to normal within 25 to 35 days after surgery if all of the tumor has been removed.
AFP is a protein found in the bloodstream of some men with testicular cancer. The level rises when the cancer is growing and falls when the cancer is shrinking or has been surgically removed, so a blood test can possibly measure the progress of the disease and success of treatment. Because of this behavior, it is referred to as a tumor marker. Elevated levels of AFP occur in 75 per cent of patients with teratocarcinoma, embryonal cell carcinoma, and yolk sac carcinoma. (However, increased levels of AFP are also found in patients with liver diseases, such as cirrhosis, acute and chronic hepatitis and hepatic necrosis. ) The serum half life of AFP is 5 to 7 days, which implies that elevated levels of AFP should fall by one half of the initial level per week and should return to normal within 25 to 35 days after surgery if all of the tumor has been removed.
| BUKHARI'S MAGIC LAB |
alpha-fetoprotein
Serum
alpha-fetoprotein <10 kU/L
Serum
alpha-fetoprotein <10 kU/L
Alpha-fetoprotein Definition from Encyclopedia Dictionaries & Glossaries
| Wikipedia English - The Free Encyclopedia |
Alpha-fetoprotein
Alpha-fetoprotein (AFP) is a molecule produced in the developing embryo and fetus. In humans, AFP levels decrease gradually after birth, reaching adult levels by 8 to 12 months. Normal adult AFP levels are low, but detectable; however, AFP has no known function in normal adults. In normal fetuses, AFP binds the hormone estradiol. AFP is measured in pregnant women, using maternal blood or amniotic fluid, as a screening test for a subset developmental abnormalities, principally open neural tube defects. It is also measured in pregnant women, other adults, and children, to detect a subset tumors, principally hepatocellular carcinoma and endodermal sinus tumors.
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