10-propargyl-10-deazaaminopterin
A substance that is being studied in the treatment of cancer. It belongs to the family of drugs called folate analogs. | ||||
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10-propargyl-10-deazaaminopterin Definition from Encyclopedia Dictionaries & Glossaries
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Pralatrexate
Pralatrexate (rINN), also known as 10-propargyl-10-deazaaminopterin, common name PDX, is a drug candidate being studied for the treatment of cancer. PDX is a folate analog inhibitor of dihydrofolate reductase. As of July 2005, it is undergoing Phase 1 and Phase 2 clinical trials for treatment of non-Hodgkin lymphoma and non-small cell lung cancer.
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